Woop woop - Sssssspirit Vyper

Screwjab Dagger is your bread and butter. It's low cooldown lets it act as your way to apply pressure at range, even with it's low initial damage. At one stack, you can proc Mystic Burst. Later, with one more stack, you'll be able to proc Tankbuster. Hit two always!

You should be looking to claim the enemy guardian ASAP, ideally before 8 minutes. With this sequence of Spirit items, we can proc Tankbuster on Dagger.

The name of the game is pick. As games go longer, you lose the ability to poke people low with Dagger bit by bit to pressure for kills. We get AOE Bola to make up for this; we're now a pick hero. We want to delete people from the timeline, so we get Curse and Silence Wave to make sure it happens. Curse is here for several reasons. #1: Cancelling ults. AOE Bola lets you cancel key ults, but it leaves us without a massive nuke. #2: Making sure Lethal Venom ALWAYS lands (unless they Counterspell but don't tell anyone). #3: Disarm and Silence good for staying alive/keeping team alive.

Extra Regen or Healing Rite for very tough lanes. You'll win when you get Bola, but you need to get there first. Counterspell and Spirit Resilience are for the same things; usually what gets you is Spirit nukes. E-Shift is a late late consideration when you already have Transcendant Cooldown. Stamina items are fine.

If your job is to kill someone, you'll want some of these. Spirit Burn is not included intentionally; Bola will waste most of its effectiveness.

If your job becomes support/disable, these are generally your best options. Range if your job is AOE control (ie stealing/securing rejuv), Slowing Hex early for Mina/Pocket/Mirage. Lightning Scroll will always hit the tick petrify ends, so it's a silly way to stun more. Disarming Hex for making M1s even more miserable.